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肺癌介绍

ID #1000

肺癌是什么

  肺癌常发生于支气管粘膜上皮亦称支气管肺癌。肺癌一般指的是肺实质部的癌症,通常不包含其他肋膜起源的中胚层肿瘤(mesothelioma),或恶性淋巴瘤(malignant lymphoma)、其他恶性肿瘤如类癌(carcinoid),或是转移自其他的肿瘤。因此以下我们所说的肺癌,是指来自于支气管(bronchial)或细支气管(bronchiolar)表皮细胞(epithelial cell)的恶性肿瘤,占了肺实质恶性肿瘤的90-95%。
  肺癌是全世界癌症中死因率最高的,1995年全世界有约60万人死于肺癌,而且每年都在上升。不可小看的是,女性患肺癌的发生率在逐年上升。肺癌多发在40岁以上,发病年龄高峰在60~79岁之间。男女患病率为2.3:1。种族、家属史与吸烟对肺癌的发病均有影响。
  肺癌起源于支气管粘膜上皮局限于基底膜内者称为原位癌癌肿,可向支气管腔内或/和临近的肺组织生长并可通过淋巴血行或经支气管转移扩散。癌瘤生长速度和转移扩散的情况与癌瘤的组织学类型分化程度等生物学特性有一定关系。
  肺癌的分布情况右肺多于左肺,上叶多于下叶,从主支气管到细支气管均可发生癌肿。起源于主支气管肺叶支气管的肺癌位置靠近肺门者称为中央型肺癌;起源于肺段支气管以下的肺癌位置在肺的周围部分者称为周围性肺癌。
  肺癌有以下两种基本类型:
  1)小细胞肺癌(SCLC)或燕麦细胞类,三分之一的肺癌患者属于这种类型;
  小细胞肺癌(SCLC)肿瘤细胞倍增时间短,进展快,常伴内分泌异常或类癌综合征;由于患者早期即发生血行转移且对放化疗敏感,故小细胞肺癌的治疗应以全身化疗为主,联合放疗和手术为主要治疗手段。综合治疗系治疗小细胞肺癌成功的关键。
  2)非小细胞肺癌(NSCLC)类,三分之一的肺癌患者属于这种类型。这种区分是相当重要的,因为对这两种类型的肺癌的治疗方案是截然不同的。小细胞肺癌患者主要用化学疗法治疗。外科治疗对这种类型肺癌患者并不起主要作用。另一方面,外科治疗主要适用于非小细胞肺癌患者。还有一种癌症类型是嗜银细胞瘤。

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=======以下为汉译英======

Of lung cancer often occurs in the bronchial mucosa also known as bronchogenic carcinoma. Of lung cancer generally refers to the substance of the Ministry of lung cancer, often do not contain other pleural mesodermal origin of tumor (mesothelioma), or malignant lymphoma (malignant lymphoma), other malignant tumors such as carcinoid tumors (carcinoid), or transfer from other tumors. Therefore, we are talking about lung cancer, the following is defined as from the bronchi (bronchial) or bronchioles (bronchiolar) epithelial cells (epithelial cell) malignant tumor, accounting for 90-95% of lung malignancies in real terms.
Lung cancer is the world's highest rate of cancer death in 1995, the world's approximately 60 million people died of lung cancer, and every year on the rise. Can not be underestimated is that the incidence of female lung cancer increased year by year. Multiple lung cancer at 40 years of age, the peak age of onset of 60 to 79 years old. Male and female prevalence rate of 2.3:1. Race, family history and smoking on the incidence of lung cancer implications.
Lung cancer originated in the bronchial mucosa epithelium confined within the basement membrane were called in situ cancer, may apply to the bronchial cavity or / and adjacent lung tissue growth and can be the blood line or through the lymphatic spread of bronchial metastasis. Carcinoid tumor growth rate and metastasis of carcinoma proliferation situation and the histological type of differentiation of biological characteristics such as a certain extent.
The distribution of lung cancer than the right lung left lung, upper lobe rather than under the leaves, from the main bronchi to the bronchioles cancer can occur. Originated in the main bronchus lobe bronchus for lung cancer were referred to as a central location close to the hilar type lung cancer; originated in the segmental bronchi of lung cancer in the following locations around the part of those in the lungs is called peripheral lung cancer.
There are two basic types of lung cancer:
A) small-cell lung cancer (SCLC) or oat cell type, one-third belong to this type of lung cancer patients;
Small cell lung cancer (SCLC) tumor cell doubling time is short, rapid development, often accompanied by endocrine abnormalities, or carcinoid syndrome; due to occur in patients with early stage hematogenous metastasis and sensitivity to the chemotherapy, so the treatment of small cell lung cancer to systemic chemotherapy should be the main , combined with radiotherapy and surgery as the main treatment. Comprehensive Therapy treatment of small cell lung cancer, the key to success.
2) non-small cell lung cancer (NSCLC) class, one-third of lung cancer patients fall into this category. This distinction is important, because these two types of lung cancer treatment programs are completely different. Is mainly used in patients with small cell lung cancer chemotherapy treatment. This type of surgical treatment on patients with lung cancer does not play a major role. On the other hand, surgical treatment is mainly applied in patients with non-small cell lung cancer. There is also a type of cancer is argyrophil cell tumors.

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更新日期: 2009-12-17 02:30
作者: : mcyclub
修订: 1.1

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