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小细胞肺癌
小细胞肺癌的治疗
对于小细胞肺癌患者,西医主要用化学疗法治疗,以全身化疗为主,配合应用放射疗法;中医治疗本病则以辨证施治为主,多配合化疗进行,也有一些用于本病的单方、验方。
小细胞肺癌中医治疗
小细胞肺癌的中医治疗主要以中西医结合为主,大多配合化疗或放疗进行,以消除化疗、放疗副作用为多见,仅有少数是直接针对肺癌本身的治疗 中药配合化疗、放疗是经临床验证的有效方法。
小细胞肺癌手术疗法
通常认为,所有经组织学、细胞学或临床诊断肺癌的患者,只要病期在Ⅱ期以前,且无绝对禁忌症,都可列为手术适应对象。但由于小细胞癌恶性程度高、转移早,一般认为不宜手术治疗。也有人提出,对于早期发现的年青人原发性肺癌,应当采用根治性外科治疗。
小细胞肺癌化疗
治疗小细胞肺癌的主要方法是化疗,化疗的疗效大多出现在治疗开始后的12周以内,其后很少能看到疗效的进一步增加。一般的说,使用中度强化化疗比常规计量化疗效果要好;但使用大剂量强化治疗并不能进一步提高疗效,反而使更多的病人需要住院治疗。对局限性小细胞肺癌的最佳治疗方案是否应为联合化疗在加胸步放疗,目前还有不同认识。关于化疗-放疗联合治疗方案中的最佳放疗时间问题,目前尚无定论。
研究表明,使用对小细胞肺癌有效的化疗药物组成联合化疗方案,所达到的有效率及生存率均优于单药化疗。近年来许多单位使用支气管动脉造影灌注药物化疗治疗小细胞肺癌,普遍报道效果好,副作用较小。
小细胞肺癌放射疗法
由于单纯用化疗治疗小细胞肺癌的胸腔局部复发率高,所以主张在化疗过程中,辅以胸腔原发灶的放疗,以提高胸内肿瘤的局部控制率。
放疗范围:原发灶及已有的淋巴转移灶,并包括较广泛的邻近淋巴引流区;近年来亦有人建议缩小照射范围,仅照射诱导化疗前临床的影像学诊断可发现的肿瘤。
放射剂量:一般认为,临床肿物为45-55Gy,亚临床灶为35-40 Gy,1.8-2.0 Gy/次,每周5次照射。
当化疗和放疗间隔使用时,放疗置于前后两个疗程化疗的的休息期内进行,依据休息时间的长短,可将总的肿瘤量分为每疗程15-20 Gy,共3疗程,或25-30 Gy,共2疗程。
干细胞移植配合小细胞肺癌化疗
自身外周血干细胞移植术的辅助下进行大剂量化疗已广泛开展。其方法是:首先采用常规化疗后取得病灶缩小者,动员外周血干细胞后用血细胞分离仪采取外周血干细胞后,再用高剂量化疗CVpP方案,化疗后24-48小时干细胞回输。
小细胞肺癌免疫疗法
有报道认为,胸腺因子对治疗肺燕麦细胞癌有良好的作用;干扰素可提高肺癌患者的免疫机能。
==== 汉译英 ====
TCM treatment of small cell lung cancer
Chinese medicine treatment of small cell lung cancer mainly Chinese and Western medicine with the main, most of them with chemotherapy or radiation therapy so as to eliminate chemotherapy, radiotherapy side effects, more common, only a few are directly aimed at the treatment of lung cancer itself, traditional Chinese medicine combined with chemotherapy, radiotherapy is a clinically verified an effective manner.
Small-cell lung cancer therapy
Generally considered that all by histology, cytology or clinical diagnosis of lung cancer patients, as long as the stage of disease at the stage Ⅱ ago, and no absolute contraindications, surgery can be classified as to adapt to the object. However, a high degree of malignant small cell carcinoma, early metastasis is generally believed that surgical treatment should not be. It was also suggested that the young people for the early detection of primary lung cancer, radical surgical treatment should be adopted.
Small cell lung cancer chemotherapy
The main treatment of small cell lung cancer is chemotherapy, chemotherapy appears mostly after the start of treatment within 12 weeks, followed by very rare to see a further increase in efficacy. In general, the use of moderately enhanced chemotherapeutic effect of chemotherapy is better than conventional measures; but high-dose intensive therapy did not further improve efficacy, but so that more patients require hospitalization. On the limitations of small cell lung cancer the best treatment whether it should be combined with chemotherapy plus chest step in radiotherapy, there are still a different consciousness. With regard to chemotherapy - radiotherapy combined with treatment programs in the best time of radiotherapy, at present not been determined.
Studies have shown that the use of small-cell lung cancer chemotherapy drug to form a coalition and effective chemotherapy, the survival rate achieved in an efficient and superior to single-agent chemotherapy. In recent years, many units, the use of bronchial arteriography infusion chemotherapy for the treatment of small cell lung cancer drugs are generally reported good results, fewer side effects.
Small-cell lung cancer radiation therapy
Thanks to the simple treatment of small cell lung cancer with chemotherapy chest high rate of local recurrence, it advocated during chemotherapy, combined with chest radiotherapy primary tumor in order to improve intrathoracic tumor local control rate.
Radiotherapy range: primary tumor and lymphatic metastasis has been, and includes a broader nearby lymphatic drainage area; in recent years, has also been suggested to narrow the scope of exposure, only induction chemotherapy before radiation clinical imaging diagnosis of a tumor can be found.
Radiation dose: is generally believed that the clinical tumor of 45-55Gy, sub-clinical lesions of 35-40 Gy ,1.8-2 .0 Gy / times, 5 times a week exposure.
When the interval of chemotherapy and radiation therapy when used in radiotherapy placed in two courses of chemotherapy before and after the rest period of time, based on the length of rest time can be divided into the total tumor volume for each course of 15-20 Gy, a total of 3 courses, or 25 -30 Gy, a total of 2 course of treatment.
Stem cell transplantation with chemotherapy for small cell lung cancer
Their own peripheral blood stem cell transplantation for the aid of high-dose chemotherapy has been widely carried out. The methods were: First, use of conventional chemotherapy and acquired lesions were reduced, the mobilization of peripheral blood stem cells in blood cell sorter to take peripheral blood stem cells, and then high-dose chemotherapy CVpP program, 24-48 hours after chemotherapy, stem-cell reinfusion.
Small-cell lung cancer immunotherapy
It has been reported that the thymus factor on the treatment of pulmonary oat cell carcinoma has a good effect; interferon can improve the immune function of patients with lung cancer.
Tags: 小细胞肺癌的治疗
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更新日期: 2009-10-27 02:58
作者: : mcyclub
修订: 1.0
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