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ID #1045
新化合物可杀死白血病癌细胞
科学家称,一种新的化合物PBOX-15能够杀死慢性淋巴细胞白血病(CLL)患者体内的癌细胞,而对健康的细胞没有影响,相关研究发表在最新一期的《癌症研究》杂志上。
爱尔兰都柏林大学圣三一学院和意大利锡耶纳大学的研究人员在55个病人提供的样本上测试了PBOX-15。研究表明,PBOX-15甚至能够杀死成年CLL患者体内的癌细胞,这种癌细胞对目前的治疗方法有抵抗力。
研究团队的负责人、圣三一学院的医学专家马克·罗拉指出,PBOX-15可以干预癌细胞的结构,它激活了一种导致细胞死亡的机制,即使这些细胞已经对化疗产生了抵抗力。
罗拉称,PBOX-15在治疗CLL方面大有潜力,但目前还处于研究的初期阶段,还有待进行进一步的实验,以观察将其用作诊疗手段时是否会出现负面影响。
CLL简称慢淋,是一种起病缓慢的淋巴细胞系中某些免疫功能不全的淋巴细胞恶性增生性疾病,在欧美白种人中较常见。
==== 汉译英 ====
Scientists say a new compound PBOX-15 can kill chronic lymphocytic leukemia (CLL) in patients with cancer cells in vivo, while no effect on healthy cells, research published in the latest issue of "Cancer Research" Journal .
Trinity College Dublin, Ireland and Italy, researchers at the University of Siena in the 55 patients tested on a sample of PBOX-15. Studies have shown that, PBOX-15 can even kill cancer cells in vivo in patients with adult CLL, which cancer cells are resistant to current therapies.
Person in charge of the research team, Trinity College pointed out that medical experts Makeluola, PBOX-15 can interfere with the structure of cancer cells, it activates a mechanism leading to cell death, even though these cells have already produced a resistance to chemotherapy.
Laura said, PBOX-15 in the treatment of CLL has much potential, but is still in early stages of research have yet to be further experiments to observe the means to be used as a treatment will not adversely affected.
CLL CLL for short, is a slow onset of some immune cell lines and malignant lymphocyte dysfunction disease, more common in Caucasians in Europe and America.
Trinity College Dublin, Ireland and Italy, researchers at the University of Siena in the 55 patients tested on a sample of PBOX-15. Studies have shown that, PBOX-15 can even kill cancer cells in vivo in patients with adult CLL, which cancer cells are resistant to current therapies.
Person in charge of the research team, Trinity College pointed out that medical experts Makeluola, PBOX-15 can interfere with the structure of cancer cells, it activates a mechanism leading to cell death, even though these cells have already produced a resistance to chemotherapy.
Laura said, PBOX-15 in the treatment of CLL has much potential, but is still in early stages of research have yet to be further experiments to observe the means to be used as a treatment will not adversely affected.
CLL CLL for short, is a slow onset of some immune cell lines and malignant lymphocyte dysfunction disease, more common in Caucasians in Europe and America.
Tags: 癌细胞
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更新日期: 2009-11-09 02:31
作者: : mcyclub
修订: 1.0
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